The main hypothesis is that the terpene profile — the dominant terpenes — of a strain work in tandem with the cannabinoid content — the amount of tetrahydrocannabinol (THC), cannabidiol (CBD), and other cannabinoids — to produce the effects people associate with different strains.
A clinical endocannabinoid deficiency has been postulated to Beryllium operative hinein certain treatment-resistant conditions (Russo 2004), and has received recent support in findings that anandamide levels are reduced over controls rein migraineurs (Sarchielli et al 2006), that a subset of fibromyalgia patients reported significant decreased pain after THC treatment (Schley et al 2006), and the active role of the ECS hinein intestinal pain and motility in irritable bowel syndrome (Massa and Monory 2006) wherein anecdotal efficacy of cannabinoid treatments have also been claimed.
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Terpenoids share a precursor with phytocannabinoids, and are all flavour and fragrance components common to human diets that have been designated Generally Recognized as Safe by the US Food and Drug Administration and other regulatory agencies. Terpenoids are quite potent, and affect animal and even human behaviour when inhaled from ambient air at serum levels rein the single digits ng·mL−1. They display unique therapeutic effects that may contribute meaningfully to the entourage effects of cannabis-based medicinal extracts. Particular focus will Beryllium placed on phytocannabinoid-terpenoid interactions that could produce synergy with respect to treatment of pain, inflammation, depression, anxiety, addiction, epilepsy, cancer, fungal and bacterial infections (including methicillin-resistant Staphylococcus aureus
An analysis of survey data from 2004 to 2014 found that passing of medical marijuana laws welches not associated with less nonmedical prescription opioid use. Thus, people with access to medical marijuana did not appear to Beryllium substituting it for prescription opioids.
Some side effects, such as diarrhea, sleepiness, abnormalities on tests of liver function, and drug interactions, appear to Beryllium due to CBD itself rather than contaminants rein CBD products; these effects were observed in some of the people who participated rein studies of Epidiolex before its approval as a drug.
Some long-term users of high doses of cannabis have developed a condition involving recurrent severe vomiting.
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Until experts understand more about how heat affects terpenes, you may want to stick with vaporizing flower at a low temperature or consuming edibles.
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